Blood Flow & Erection Science

NO pathway, endothelial function, smooth-muscle relaxation, and practical lifestyle/nutrition levers to support circulation.

Updated: · by PenileBoost

Nitric oxide signaling and vessel dilation diagram
Signal → NO → Smooth-muscle relaxation → Arterial inflow ↑ & Venous trapping → Erection

1) Physiology 101

Parasympathetic signaling triggers nitric oxide (NO) release → cGMP ↑ → cavernosal smooth muscle relaxes → arterial inflow rises and venous outflow is partially trapped against the tunica, producing rigidity.

PDE5 note: PDE5 inhibitors slow cGMP breakdown. Use only under medical supervision, and do not combine with nitrate medications.

2) Endothelial Health


3) Lifestyle Levers


4) Nutrition & Supplements

Medication warning: Do not take nitrate drugs with PDE5 inhibitors (risk of hypotension).


5) Training & Circulation


6) Health Checks


7) FAQ

NO-supporting foods vs. arginine/citrulline?
Dietary nitrates (beet/arugula) use the nitrate → nitrite → NO pathway, while arginine/citrulline provide substrate for eNOS—both can contribute to NO production via different routes.
Does stress really matter?

Yes. Elevated sympathetic tone increases vasoconstriction and interferes with NO-mediated relaxation. Sleep, aerobic work, and breathing practices help restore balance.

Next: Jelqing Basics · Manual Stretching · Recovery & Safety


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